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An A(2A )adenosine receptor agonist, ATL313, reduces inflammation and improves survival in murine sepsis models
BACKGROUND: The pathophysiology of sepsis is due in part to early systemic inflammation. Here we describe molecular and cellular responses, as well as survival, in A(2A )adenosine receptor (AR) agonist treated and untreated animals during experimental sepsis. METHODS: Sepsis was induced in mice by i...
Autores principales: | Moore, Christopher C, Martin, Edward N, Lee, Grace H, Obrig, Tom, Linden, Joel, Scheld, W Michael |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2588444/ https://www.ncbi.nlm.nih.gov/pubmed/18937852 http://dx.doi.org/10.1186/1471-2334-8-141 |
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