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Regulating amyloid precursor protein synthesis through an internal ribosomal entry site

Expression of amyloid precursor protein (APP) is critical to the etiology of Alzheimer's disease (AD). Consequently, regulating APP expression is one approach to block disease progression. To this end, APP can be targeted at the levels of transcription, translation, and protein stability. Littl...

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Detalles Bibliográficos
Autores principales: Beaudoin, Monique E., Poirel, Vincent-Joseph, Krushel, Leslie A.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2588504/
https://www.ncbi.nlm.nih.gov/pubmed/18953033
http://dx.doi.org/10.1093/nar/gkn792