Aptamers that recognize drug-resistant HIV-1 reverse transcriptase

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Drug-resistant variants of HIV-1 reverse transcriptase (RT) are also known to be resistant to anti-RT RNA aptamers. In order to be able to develop diagnostics and therapies that can focus on otherwise drug-resistant viruses, we have isolated two aptamers against a well-known, drug-resistant HIV-1 RT...

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Detalles Bibliográficos
Autores principales: Li, Na, Wang, Yuxuan, Pothukuchy, Arti, Syrett, Angel, Husain, Naeem, Gopalakrisha, Siddharth, Kosaraju, Pradeepa, Ellington, Andrew D.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2588506/
https://www.ncbi.nlm.nih.gov/pubmed/18948292
http://dx.doi.org/10.1093/nar/gkn775

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2588506/
https://www.ncbi.nlm.nih.gov/pubmed/18948292
http://dx.doi.org/10.1093/nar/gkn775

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