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The antiretroviral potency of APOBEC1 deaminase from small animal species

Although the role of the APOBEC3-dependent retroelement restriction system as an intrinsic immune defense against human immunodeficiency virus type1 (HIV-1) infection is becoming clear, only the rat ortholog of mammalian APOBEC1s (A1) thus far has been shown to possess antiviral activity. Here, we c...

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Detalles Bibliográficos
Autores principales: Ikeda, Terumasa, Ohsugi, Takeo, Kimura, Tetsuya, Matsushita, Shuzo, Maeda, Yosuke, Harada, Shinji, Koito, Atsushi
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2588513/
https://www.ncbi.nlm.nih.gov/pubmed/18971252
http://dx.doi.org/10.1093/nar/gkn802