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Drosophila bloom helicase maintains genome integrity by inhibiting recombination between divergent DNA sequences

DNA double strand breaks (DSB) can be repaired either via a sequence independent joining of DNA ends or via homologous recombination. We established a detection system in Drosophila melanogaster to investigate the impact of sequence constraints on the usage of the homology based DSB repair via singl...

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Detalles Bibliográficos
Autores principales: Kappeler, Michael, Kranz, Elisabeth, Woolcock, Katrina, Georgiev, Oleg, Schaffner, Walter
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2588521/
https://www.ncbi.nlm.nih.gov/pubmed/18978019
http://dx.doi.org/10.1093/nar/gkn793