The Host-Dependent Interaction of α-Importins with Influenza PB2 Polymerase Subunit Is Required for Virus RNA Replication

The influenza virus polymerase is formed by the PB1, PB2 and PA subunits and is required for virus transcription and replication in the nucleus of infected cells. As PB2 is a relevant host-range determinant we expressed a TAP-tagged PB2 in human cells and isolated intracellular complexes. Alpha-impo...

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Detalles Bibliográficos
Autores principales: Resa-Infante, Patricia, Jorba, Núria, Zamarreño, Noelia, Fernández, Yolanda, Juárez, Silvia, Ortín, Juan
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2588535/
https://www.ncbi.nlm.nih.gov/pubmed/19066626
http://dx.doi.org/10.1371/journal.pone.0003904

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2588535/
https://www.ncbi.nlm.nih.gov/pubmed/19066626
http://dx.doi.org/10.1371/journal.pone.0003904

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