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Association Rate Constants of Ras-Effector Interactions Are Evolutionarily Conserved
Evolutionary conservation of protein interaction properties has been shown to be a valuable indication for functional importance. Here we use homology interface modeling of 10 Ras-effector complexes by selecting ortholog proteins from 12 organisms representing the major eukaryotic branches, except p...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2588540/ https://www.ncbi.nlm.nih.gov/pubmed/19096503 http://dx.doi.org/10.1371/journal.pcbi.1000245 |