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Unraveling the biochemistry and provenance of pupylation: a prokaryotic analog of ubiquitination

Recently Mycobacterium tuberculosis was shown to possess a novel protein modification, in which a small protein Pup is conjugated to the epsilon-amino groups of lysines in target proteins. Analogous to ubiquitin modification in eukaryotes, this remarkable modification recruits proteins for degradati...

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Detalles Bibliográficos
Autores principales: Iyer, Lakshminarayan M, Burroughs, AM, Aravind, L
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2588565/
https://www.ncbi.nlm.nih.gov/pubmed/18980670
http://dx.doi.org/10.1186/1745-6150-3-45