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Unraveling the biochemistry and provenance of pupylation: a prokaryotic analog of ubiquitination
Recently Mycobacterium tuberculosis was shown to possess a novel protein modification, in which a small protein Pup is conjugated to the epsilon-amino groups of lysines in target proteins. Analogous to ubiquitin modification in eukaryotes, this remarkable modification recruits proteins for degradati...
Autores principales: | Iyer, Lakshminarayan M, Burroughs, AM, Aravind, L |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2588565/ https://www.ncbi.nlm.nih.gov/pubmed/18980670 http://dx.doi.org/10.1186/1745-6150-3-45 |
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