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Astrocytes play a key role in activation of microglia by persistent Borna disease virus infection

Neonatal Borna disease virus (BDV) infection of the rat brain is associated with microglial activation and damage to certain neuronal populations. Since persistent BDV infection of neurons is nonlytic in vitro, activated microglia have been suggested to be responsible for neuronal cell death in vivo...

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Detalles Bibliográficos
Autores principales: Ovanesov, Mikhail V, Ayhan, Yavuz, Wolbert, Candie, Moldovan, Krisztina, Sauder, Christian, Pletnikov, Mikhail V
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2588577/
https://www.ncbi.nlm.nih.gov/pubmed/19014432
http://dx.doi.org/10.1186/1742-2094-5-50