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Promoter Hypermethylation-mediated Inactivation of LRRC4 in Gliomas
BACKGROUND: Leucine-rich repeat C4 protein (LRRC4) is a new member of the leucine-rich repeat (LRR) superfamily. It is not only a brain-specific gene but also a novel candidate for tumor suppression. LRRC4 inactivation is commonly found in glioma cell lines and primary glioma biopsies. However, litt...
Autores principales: | , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2588634/ https://www.ncbi.nlm.nih.gov/pubmed/18976507 http://dx.doi.org/10.1186/1471-2199-9-99 |