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Promoter Hypermethylation-mediated Inactivation of LRRC4 in Gliomas

BACKGROUND: Leucine-rich repeat C4 protein (LRRC4) is a new member of the leucine-rich repeat (LRR) superfamily. It is not only a brain-specific gene but also a novel candidate for tumor suppression. LRRC4 inactivation is commonly found in glioma cell lines and primary glioma biopsies. However, litt...

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Detalles Bibliográficos
Autores principales:	Zhang, Zuping, Li, Dan, Wu, Minghua, Xiang, Bo, Wang, Li, Zhou, Ming, Chen, Pan, Li, Xiaoling, Shen, Shourong, Li, Guiyuan
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2588634/ https://www.ncbi.nlm.nih.gov/pubmed/18976507 http://dx.doi.org/10.1186/1471-2199-9-99

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