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Cyclophosphamide-Induced Cystitis Increases Bladder CXCR4 Expression and CXCR4-Macrophage Migration Inhibitory Factor Association

BACKGROUND: Macrophage migration inhibitory factor (MIF) is a pro-inflammatory cytokine involved in cystitis and a non-cognate ligand of the chemokine receptor CXCR4 in vitro. We studied whether CXCR4-MIF associations occur in rat bladder and the effect of experimental cystitis. METHODS AND FINDINGS...

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Detalles Bibliográficos
Autores principales: Vera, Pedro L., Iczkowski, Kenneth A., Wang, Xihai, Meyer-Siegler, Katherine L.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2588654/
https://www.ncbi.nlm.nih.gov/pubmed/19066630
http://dx.doi.org/10.1371/journal.pone.0003898