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Topoisomerase 3α and RMI1 Suppress Somatic Crossovers and Are Essential for Resolution of Meiotic Recombination Intermediates in Arabidopsis thaliana

Topoisomerases are enzymes with crucial functions in DNA metabolism. They are ubiquitously present in prokaryotes and eukaryotes and modify the steady-state level of DNA supercoiling. Biochemical analyses indicate that Topoisomerase 3α (TOP3α) functions together with a RecQ DNA helicase and a third...

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Detalles Bibliográficos
Autores principales: Hartung, Frank, Suer, Stefanie, Knoll, Alexander, Wurz-Wildersinn, Rebecca, Puchta, Holger
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2588661/
https://www.ncbi.nlm.nih.gov/pubmed/19096507
http://dx.doi.org/10.1371/journal.pgen.1000285