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A Mathematical Framework for the Selection of an Optimal Set of Peptides for Epitope-Based Vaccines

Epitope-based vaccines (EVs) have a wide range of applications: from therapeutic to prophylactic approaches, from infectious diseases to cancer. The development of an EV is based on the knowledge of target-specific antigens from which immunogenic peptides, so-called epitopes, are derived. Such epito...

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Detalles Bibliográficos
Autores principales: Toussaint, Nora C., Dönnes, Pierre, Kohlbacher, Oliver
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2588662/
https://www.ncbi.nlm.nih.gov/pubmed/19112482
http://dx.doi.org/10.1371/journal.pcbi.1000246