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Is alopecia areata an autoimmune-response against melanogenesis-related proteins, exposed by abnormal MHC class I expression in the anagen hair bulb?

The etiology of alopecia areata (AA), a putative autoimmune disease characterized by sudden hair loss, has remained obscure. It is not understood, how the characteristic inflammatory infiltrate that selectively attacks anagen hair follicles in AA is generated. We hypothesize that this reflects an un...

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Detalles Bibliográficos
Autores principales: Paus, R., Slominski, A., Czarnetzki, B. M.
Formato: Texto
Lenguaje:English
Publicado: Yale Journal of Biology and Medicine 1993
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2588848/
https://www.ncbi.nlm.nih.gov/pubmed/7716973