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Interaction of proton pump inhibitors with cytochromes P450: consequences for drug interactions.
Omeprazole, lansoprazole and pantoprazole are metabolized by several human cytochromes P450, most prominently by CYP2C19 and CYP3A4. Only pantoprazole is also metabolized by a sulfotransferase. Differences in the quantitative contribution of these enzymes and in the relative affinities of the substr...
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| Formato: | Texto |
| Lenguaje: | English |
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Yale Journal of Biology and Medicine
1996
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2589004/ https://www.ncbi.nlm.nih.gov/pubmed/9165689 |