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Progress with proton pump inhibition.
The proton pump, a H+/K(+)-ATPase located on the secretory canalicular membrane of the parietal cell, forms the final pathway for gastric acid secretion. Omeprazole is concentrated in the secretory canaliculus, where it is converted to its active form, which binds covalently with the H+/K(+)-ATPase,...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Yale Journal of Biology and Medicine
1992
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2589777/ https://www.ncbi.nlm.nih.gov/pubmed/1341069 |