A new model defines the minimal set of polymorphism in HLA-DQ and -DR that determines susceptibility and resistance to autoimmune diabetes

BACKGROUND: The mechanism underlying autoimmune diabetes has been difficult to define. There is a strong genetic contribution and numerous studies associate the major histocompatibility complex, especially the class II region, with predisposition or resistance. However, how these molecules are impli...

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Detalles Bibliográficos
Autores principales: Parry, Christian S, Brooks, Bernard R
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Hypothesis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2590596/
https://www.ncbi.nlm.nih.gov/pubmed/18854049
http://dx.doi.org/10.1186/1745-6150-3-42

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2590596/
https://www.ncbi.nlm.nih.gov/pubmed/18854049
http://dx.doi.org/10.1186/1745-6150-3-42

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