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A new model defines the minimal set of polymorphism in HLA-DQ and -DR that determines susceptibility and resistance to autoimmune diabetes
BACKGROUND: The mechanism underlying autoimmune diabetes has been difficult to define. There is a strong genetic contribution and numerous studies associate the major histocompatibility complex, especially the class II region, with predisposition or resistance. However, how these molecules are impli...
Autores principales: | Parry, Christian S, Brooks, Bernard R |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2590596/ https://www.ncbi.nlm.nih.gov/pubmed/18854049 http://dx.doi.org/10.1186/1745-6150-3-42 |
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