Rapid analysis of heterogeneously methylated DNA using digital methylation-sensitive high resolution melting: application to the CDKN2B (p15) gene

BACKGROUND: Methylation-sensitive high resolution melting (MS-HRM) methodology is able to recognise heterogeneously methylated sequences by their characteristic melting profiles. To further analyse heterogeneously methylated sequences, we adopted a digital approach to MS-HRM (dMS-HRM) that involves...

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Detalles Bibliográficos
Autores principales: Candiloro, Ida LM, Mikeska, Thomas, Hokland, Peter, Dobrovic, Alexander
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Methodology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2590600/
https://www.ncbi.nlm.nih.gov/pubmed/19014416
http://dx.doi.org/10.1186/1756-8935-1-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2590600/
https://www.ncbi.nlm.nih.gov/pubmed/19014416
http://dx.doi.org/10.1186/1756-8935-1-7

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