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Rapid analysis of heterogeneously methylated DNA using digital methylation-sensitive high resolution melting: application to the CDKN2B (p15) gene

BACKGROUND: Methylation-sensitive high resolution melting (MS-HRM) methodology is able to recognise heterogeneously methylated sequences by their characteristic melting profiles. To further analyse heterogeneously methylated sequences, we adopted a digital approach to MS-HRM (dMS-HRM) that involves...

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Detalles Bibliográficos
Autores principales:	Candiloro, Ida LM, Mikeska, Thomas, Hokland, Peter, Dobrovic, Alexander
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2008
Materias:	Methodology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2590600/ https://www.ncbi.nlm.nih.gov/pubmed/19014416 http://dx.doi.org/10.1186/1756-8935-1-7

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