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Search Algorithms as a Framework for the Optimization of Drug Combinations

Combination therapies are often needed for effective clinical outcomes in the management of complex diseases, but presently they are generally based on empirical clinical experience. Here we suggest a novel application of search algorithms—originally developed for digital communication—modified to o...

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Detalles Bibliográficos
Autores principales: Calzolari, Diego, Bruschi, Stefania, Coquin, Laurence, Schofield, Jennifer, Feala, Jacob D., Reed, John C., McCulloch, Andrew D., Paternostro, Giovanni
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2590660/
https://www.ncbi.nlm.nih.gov/pubmed/19112483
http://dx.doi.org/10.1371/journal.pcbi.1000249