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The Kv2.1 K(+ )channel targets to the axon initial segment of hippocampal and cortical neurons in culture and in situ

BACKGROUND: The Kv2.1 delayed-rectifier K(+ )channel regulates membrane excitability in hippocampal neurons where it targets to dynamic cell surface clusters on the soma and proximal dendrites. In the past, Kv2.1 has been assumed to be absent from the axon initial segment. RESULTS: Transfected and e...

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Detalles Bibliográficos
Autores principales: Sarmiere, Patrick D, Weigle, Cecile M, Tamkun, Michael M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2592246/
https://www.ncbi.nlm.nih.gov/pubmed/19014551
http://dx.doi.org/10.1186/1471-2202-9-112