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Global DNA Hypomethylation Is Associated with High Serum-Persistent Organic Pollutants in Greenlandic Inuit

BACKGROUND: Persistent organic pollutants (POPs) may influence epigenetic mechanisms; therefore, they could affect chromosomal stability and gene expression. DNA methylation, an epigenetic mechanism, has been associated with cancer initiation and progression. Greenlandic Inuit have some of the highe...

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Detalles Bibliográficos
Autores principales: Rusiecki, Jennifer A., Baccarelli, Andrea, Bollati, Valentina, Tarantini, Letizia, Moore, Lee E., Bonefeld-Jorgensen, Eva C.
Formato: Texto
Lenguaje:English
Publicado: National Institute of Environmental Health Sciences 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2592276/
https://www.ncbi.nlm.nih.gov/pubmed/19057709
http://dx.doi.org/10.1289/ehp.11338