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Modeling a Snap-Action, Variable-Delay Switch Controlling Extrinsic Cell Death
When exposed to tumor necrosis factor (TNF) or TNF-related apoptosis-inducing ligand (TRAIL), a closely related death ligand and investigational therapeutic, cells enter a protracted period of variable duration in which only upstream initiator caspases are active. A subsequent and sudden transition...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2592357/ https://www.ncbi.nlm.nih.gov/pubmed/19053173 http://dx.doi.org/10.1371/journal.pbio.0060299 |