Frequent Toggling between Alternative Amino Acids Is Driven by Selection in HIV-1

Host immune responses against infectious pathogens exert strong selective pressures favouring the emergence of escape mutations that prevent immune recognition. Escape mutations within or flanking functionally conserved epitopes can occur at a significant cost to the pathogen in terms of its ability...

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Detalles Bibliográficos
Autores principales: Delport, Wayne, Scheffler, Konrad, Seoighe, Cathal
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2592544/
https://www.ncbi.nlm.nih.gov/pubmed/19096508
http://dx.doi.org/10.1371/journal.ppat.1000242

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2592544/
https://www.ncbi.nlm.nih.gov/pubmed/19096508
http://dx.doi.org/10.1371/journal.ppat.1000242

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