Acute Myeloid Leukemia-Targeted Toxin Activates Both Apoptotic and Necroptotic Death Mechanisms

BACKGROUND: Acute myelogenous leukemia (AML) is the second most common leukemia with approximately 13,410 new cases and 8,990 deaths annually in the United States. A novel fusion toxin treatment, diphtheria toxin GM-CSF (DT-GMCSF) has been shown to selectively eliminate leukemic repopulating cells t...

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Detalles Bibliográficos
Autores principales: Horita, Henrick, Frankel, Arthur E., Thorburn, Andrew
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2592546/
https://www.ncbi.nlm.nih.gov/pubmed/19079542
http://dx.doi.org/10.1371/journal.pone.0003909

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2592546/
https://www.ncbi.nlm.nih.gov/pubmed/19079542
http://dx.doi.org/10.1371/journal.pone.0003909

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