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Stat3 and c-Myc Genome-Wide Promoter Occupancy in Embryonic Stem Cells

Embryonic stem (ES) cell pluripotency is regulated in part by transcription factor (TF) pathways that maintain self-renewal and inhibit differentiation. Stat3 and c-Myc TFs are essential for maintaining mouse ES cell self-renewal. c-Myc, together with Oct4, Sox2, and Klf4, is a reprogramming factor....

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Detalles Bibliográficos
Autores principales: Kidder, Benjamin L., Yang, Jim, Palmer, Stephen
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2592696/
https://www.ncbi.nlm.nih.gov/pubmed/19079543
http://dx.doi.org/10.1371/journal.pone.0003932