Cargando…
Modeling synthetic lethality
BACKGROUND: Synthetic lethality defines a genetic interaction where the combination of mutations in two or more genes leads to cell death. The implications of synthetic lethal screens have been discussed in the context of drug development as synthetic lethal pairs could be used to selectively kill c...
| Autores principales: | , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2008
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2592713/ https://www.ncbi.nlm.nih.gov/pubmed/18789146 http://dx.doi.org/10.1186/gb-2008-9-9-r135 |