Segmentation-based detection of allelic imbalance and loss-of-heterozygosity in cancer cells using whole genome SNP arrays

We present a strategy for detection of loss-of-heterozygosity and allelic imbalance in cancer cells from whole genome single nucleotide polymorphism genotyping data. Using a dilution series of a tumor cell line mixed with its paired normal cell line and data generated on Affymetrix and Illumina plat...

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Detalles Bibliográficos
Autores principales: Staaf, Johan, Lindgren, David, Vallon-Christersson, Johan, Isaksson, Anders, Göransson, Hanna, Juliusson, Gunnar, Rosenquist, Richard, Höglund, Mattias, Borg, Åke, Ringnér, Markus
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2592714/
https://www.ncbi.nlm.nih.gov/pubmed/18796136
http://dx.doi.org/10.1186/gb-2008-9-9-r136

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2592714/
https://www.ncbi.nlm.nih.gov/pubmed/18796136
http://dx.doi.org/10.1186/gb-2008-9-9-r136

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