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Model-driven analysis of experimentally determined growth phenotypes for 465 yeast gene deletion mutants under 16 different conditions

BACKGROUND: Understanding the response of complex biochemical networks to genetic perturbations and environmental variability is a fundamental challenge in biology. Integration of high-throughput experimental assays and genome-scale computational methods is likely to produce insight otherwise unreac...

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Detalles Bibliográficos
Autores principales: Snitkin, Evan S, Dudley, Aimée M, Janse, Daniel M, Wong, Kaisheen, Church, George M, Segrè, Daniel
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2592718/
https://www.ncbi.nlm.nih.gov/pubmed/18808699
http://dx.doi.org/10.1186/gb-2008-9-9-r140