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Pressure support ventilation attenuates ventilator-induced protein modifications in the diaphragm

INTRODUCTION: Controlled mechanical ventilation (CMV) induces profound modifications of diaphragm protein metabolism, including muscle atrophy and severe ventilator-induced diaphragmatic dysfunction. Diaphragmatic modifications could be decreased by spontaneous breathing. We hypothesized that mechan...

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Detalles Bibliográficos
Autores principales: Futier, Emmanuel, Constantin, Jean-Michel, Combaret, Lydie, Mosoni, Laurent, Roszyk, Laurence, Sapin, Vincent, Attaix, Didier, Jung, Boris, Jaber, Samir, Bazin, Jean-Etienne
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2592744/
https://www.ncbi.nlm.nih.gov/pubmed/18786263
http://dx.doi.org/10.1186/cc7010