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Targeting histone deacetylase activity in rheumatoid arthritis and asthma as prototypes of inflammatory disease: should we keep our HATs on?

Cellular activation, proliferation and survival in chronic inflammatory diseases is regulated not only by engagement of signal trans-duction pathways that modulate transcription factors required for these processes, but also by epigenetic regulation of transcription factor access to gene promoter re...

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Detalles Bibliográficos
Autores principales: Grabiec, Aleksander M, Tak, Paul P, Reedquist, Kris A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2592777/
https://www.ncbi.nlm.nih.gov/pubmed/18983693
http://dx.doi.org/10.1186/ar2489