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Targeting histone deacetylase activity in rheumatoid arthritis and asthma as prototypes of inflammatory disease: should we keep our HATs on?
Cellular activation, proliferation and survival in chronic inflammatory diseases is regulated not only by engagement of signal trans-duction pathways that modulate transcription factors required for these processes, but also by epigenetic regulation of transcription factor access to gene promoter re...
Autores principales: | Grabiec, Aleksander M, Tak, Paul P, Reedquist, Kris A |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2592777/ https://www.ncbi.nlm.nih.gov/pubmed/18983693 http://dx.doi.org/10.1186/ar2489 |
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