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Reduced proportions of natural killer T cells are present in the relatives of lupus patients and are associated with autoimmunity

INTRODUCTION: Systemic lupus erythematosus is a genetically complex disease. Currently, the precise allelic polymorphisms associated with this condition remain largely unidentified. In part this reflects the fact that multiple genes, each having a relatively minor effect, act in concert to produce d...

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Detalles Bibliográficos
Autores principales: Wither, Joan, Cai, Yong-chun, Lim, Sooyeol, McKenzie, Tamara, Roslin, Nicole, Claudio, Jaime O, Cooper, Glinda S, Hudson, Thomas J, Paterson, Andrew D, Greenwood, Celia MT, Gladman, Dafna, Pope, Janet, Pineau, Christian A, Smith, C Douglas, Hanly, John G, Peschken, Christine, Boire, Gilles, Fortin, Paul R
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2592790/
https://www.ncbi.nlm.nih.gov/pubmed/18783591
http://dx.doi.org/10.1186/ar2505