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Epitope spreading to citrullinated antigens in mouse models of autoimmune arthritis and demyelination
INTRODUCTION: Anti-citrullinated protein antibodies have a diagnostic role in rheumatoid arthritis (RA); however, little is known about their origins and contribution to pathogenesis. Citrullination is the post-translational conversion of arginine to citrulline by peptidyl arginine deiminase, and in...
Autores principales: | , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2592807/ https://www.ncbi.nlm.nih.gov/pubmed/18826638 http://dx.doi.org/10.1186/ar2523 |