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Epitope spreading to citrullinated antigens in mouse models of autoimmune arthritis and demyelination

INTRODUCTION: Anti-citrullinated protein antibodies have a diagnostic role in rheumatoid arthritis (RA); however, little is known about their origins and contribution to pathogenesis. Citrullination is the post-translational conversion of arginine to citrulline by peptidyl arginine deiminase, and in...

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Detalles Bibliográficos
Autores principales:	Kidd, Brian A, Ho, Peggy P, Sharpe, Orr, Zhao, Xiaoyan, Tomooka, Beren H, Kanter, Jennifer L, Steinman, Lawrence, Robinson, William H
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2592807/ https://www.ncbi.nlm.nih.gov/pubmed/18826638 http://dx.doi.org/10.1186/ar2523

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