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Toll-like receptor homolog RP105 modulates the antigen-presenting cell function and regulates the development of collagen-induced arthritis

INTRODUCTION: RP105 is a Toll-like receptor homolog expressed on B cells, dendritic cells (DCs), and macrophages. We investigated the role of RP105 in the development of collagen-induced arthritis (CIA). METHODS: CIA was induced in RP105-deficient DBA/1 mice and the incidence and arthritis index wer...

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Detalles Bibliográficos
Autores principales: Tada, Yoshifumi, Koarada, Syuichi, Morito, Fumitaka, Mitamura, Mio, Inoue, Hisako, Suematsu, Rie, Ohta, Akihide, Miyake, Kensuke, Nagasawa, Kohei
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2592811/
https://www.ncbi.nlm.nih.gov/pubmed/18847495
http://dx.doi.org/10.1186/ar2529