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Genome-wide analysis reveals a cell cycle–dependent mechanism controlling centromere propagation

Centromeres are the structural and functional foundation for kinetochore formation, spindle attachment, and chromosome segregation. In this study, we isolated factors required for centromere propagation using genome-wide RNA interference screening for defects in centromere protein A (CENP-A; centrom...

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Detalles Bibliográficos
Autores principales: Erhardt, Sylvia, Mellone, Barbara G., Betts, Craig M., Zhang, Weiguo, Karpen, Gary H., Straight, Aaron F.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2592830/
https://www.ncbi.nlm.nih.gov/pubmed/19047461
http://dx.doi.org/10.1083/jcb.200806038