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Structural basis for midbody targeting of spastin by the ESCRT-III protein CHMP1B

The ESCRT machinery, including ESCRT-III, localizes to the midbody and participates in the membrane abscission step of cytokinesis. The ESCRT-III protein CHMP1B is required for recruitment of the MIT domain-containing protein spastin, a microtubule severing enzyme, to the midbody. The 2.5 Å structur...

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Detalles Bibliográficos
Autores principales: Yang, Dong, Rismanchi, Neggy, Renvoisé, Benoît, Lippincott-Schwartz, Jennifer, Blackstone, Craig, Hurley, James H.
Formato: Texto
Lenguaje:English
Publicado: 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2593743/
https://www.ncbi.nlm.nih.gov/pubmed/18997780
http://dx.doi.org/10.1038/nsmb.1512