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Structural basis for midbody targeting of spastin by the ESCRT-III protein CHMP1B
The ESCRT machinery, including ESCRT-III, localizes to the midbody and participates in the membrane abscission step of cytokinesis. The ESCRT-III protein CHMP1B is required for recruitment of the MIT domain-containing protein spastin, a microtubule severing enzyme, to the midbody. The 2.5 Å structur...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2593743/ https://www.ncbi.nlm.nih.gov/pubmed/18997780 http://dx.doi.org/10.1038/nsmb.1512 |