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Alternative Isoform Regulation in Human Tissue Transcriptomes

Through alternative processing of pre-mRNAs, individual mammalian genes often produce multiple mRNA and protein isoforms that may have related, distinct or even opposing functions. Here we report an in-depth analysis of 15 diverse human tissue and cell line transcriptomes based on deep sequencing of...

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Detalles Bibliográficos
Autores principales: Wang, Eric T., Sandberg, Rickard, Luo, Shujun, Khrebtukova, Irina, Zhang, Lu, Mayr, Christine, Kingsmore, Stephen F., Schroth, Gary P., Burge, Christopher B.
Formato: Texto
Lenguaje:English
Publicado: 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2593745/
https://www.ncbi.nlm.nih.gov/pubmed/18978772
http://dx.doi.org/10.1038/nature07509