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Determination of thymic function directly from peripheral blood: A validated modification to an established method()

The thymus contributes naïve, self MHC reactive, self tolerant T cells to the peripheral immune system throughout life, albeit with a log-linear decline with age. Quantification of thymic function is clinically relevant in the setting of lymphoablation, but a phenotypic marker distinguishing recent...

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Detalles Bibliográficos
Autores principales: Lorenzi, A.R., Patterson, A.M., Pratt, A., Jefferson, M., Chapman, C.E., Ponchel, F., Isaacs, J.D.
Formato: Texto
Lenguaje:English
Publicado: Elsevier 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2593795/
https://www.ncbi.nlm.nih.gov/pubmed/18854192
http://dx.doi.org/10.1016/j.jim.2008.09.013