Cargando…
Determination of thymic function directly from peripheral blood: A validated modification to an established method()
The thymus contributes naïve, self MHC reactive, self tolerant T cells to the peripheral immune system throughout life, albeit with a log-linear decline with age. Quantification of thymic function is clinically relevant in the setting of lymphoablation, but a phenotypic marker distinguishing recent...
Autores principales: | Lorenzi, A.R., Patterson, A.M., Pratt, A., Jefferson, M., Chapman, C.E., Ponchel, F., Isaacs, J.D. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2008
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2593795/ https://www.ncbi.nlm.nih.gov/pubmed/18854192 http://dx.doi.org/10.1016/j.jim.2008.09.013 |
Ejemplares similares
-
Corrigendum to “Determination of thymic function directly from peripheral blood: A validated modification to an established method” [J. Immunol. Methods 2008 339(2):185–94]
por: Lorenzi, A.R., et al.
Publicado: (2009) -
A revised assay for the measurement of T-cell receptor excision circles as a quantitative measure of thymic function in systemic lupus erythematosus
por: Lorenzi, AR, et al.
Publicado: (2005) -
Thymic function in juvenile idiopathic arthritis
por: Lorenzi, A R, et al.
Publicado: (2008) -
Improvement of T-cell function in rheumatoid arthritis (RA) patients in clinical remission is associated with the recovery of IL-7 expression and depends on a familial history of RA
por: Ponchel, F, et al.
Publicado: (2005) -
T-bet expression in rheumatoid arthritis patients with early, disease-modifying anti-rheumatic drug naïve disease is low and correlates with low levels of IL-7 and T-cell dysfunctions
por: Ponchel, F, et al.
Publicado: (2005)