Focal distortion of the nuclear envelope by huntingtin aggregates revealed by lamin immunostaining

Huntington’s disease is an autosomal dominant neurodegenerative disorder caused by the expansion of a polyglutamine repeat tract in the huntingtin protein. Polyglutamine-expanded huntingtin forms intranuclear as well as perinuclear inclusion bodies. Perinuclear aggregates formed by polyglutamine-exp...

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Detalles Bibliográficos
Autores principales: Chapple, J. Paul, Bros-Facer, Virginie, Butler, Rachel, Gallo, Jean-Marc
Formato: Texto
Lenguaje:English
Publicado: Elsevier Scientific Publishers Ireland 2008
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2593798/
https://www.ncbi.nlm.nih.gov/pubmed/18840504
http://dx.doi.org/10.1016/j.neulet.2008.09.075

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2593798/
https://www.ncbi.nlm.nih.gov/pubmed/18840504
http://dx.doi.org/10.1016/j.neulet.2008.09.075

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