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Preferential Inhibition of Herpes-Group Viruses by Phosphonoacetic Acid: Effect on Virus DNA Synthesis and Virus-Induced DNA Polymerase Activity

In tissue culture phosphonoacetic acid (PAA) specifically inhibited DNA synthesis of human cytomegalovirus (CMV), murine CMV, simian CMV, Epstein-Barr virus, and Herpesvirus saimiri. Fifty to one hundred micrograms per milliliter PAA completely inhibited viral DNA synthesis with no significant damag...

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Detalles Bibliográficos
Autores principales: Huang, Eng-Shang, Huang, Chien-Hui, Huong, Shu-Mei, Selgrade, Maryjane
Formato: Texto
Lenguaje:English
Publicado: 1976
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2595326/
https://www.ncbi.nlm.nih.gov/pubmed/960726