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Erythropoietin-mediated erythrocytosis in rodents after intrarenal injection of nickel subsulfide.

Rats and guinea pigs developed pronounced erythrocytosis at one to four months after unilateral intrarenal (ir) injection of nickel subsulfide (Ni3S2). For example, at two months after ir administration of Ni3S2 (5 mg) to rats, blood hematocrit values averaged 70 +/- 3 percent (p less than 0.001 vs....

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Detalles Bibliográficos
Autores principales: Sunderman, F. W., Hopfer, S. M., Reid, M. C., Shen, S. K., Kevorkian, C. B.
Formato: Texto
Lenguaje:English
Publicado: Yale Journal of Biology and Medicine 1982
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2596014/
https://www.ncbi.nlm.nih.gov/pubmed/6291262