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Identification of human thioredoxin as a novel IFN-gamma-induced factor: Mechanism of induction and its role in cytokine production

BACKGROUND: IFN-γ is a multifunctional peptide with a potent immune defense function which is also known as a prototypic Th1 cytokine. While screening for genes differentially expressed by Th1 and Th2 cytokines, human thioredoxin was identified as a novel target gene induced by IFN-γ. The mechanism...

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Detalles Bibliográficos
Autores principales: Kim, Seol-Hee, Oh, Jiyoung, Choi, Ja-Young, Jang, Ji-Young, Kang, Myoung-Wha, Lee, Choong-Eun
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2596082/
https://www.ncbi.nlm.nih.gov/pubmed/18983687
http://dx.doi.org/10.1186/1471-2172-9-64