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Interleukin-1beta and tumour necrosis factor-alpha impede neutral lipid turnover in macrophage-derived foam cells

BACKGROUND: Pro-inflammatory cytokines can affect intracellular lipid metabolism. A variety of effects have been described for different cell types; hepatocyte lipid turnover pathways are inhibited during inflammation, whereas interleukin-1β (IL-1β) reduces intracellular cholesterol levels in fibrob...

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Detalles Bibliográficos
Autores principales: Persson, Jenny, Nilsson, Jan, Lindholm, Marie W
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2596083/
https://www.ncbi.nlm.nih.gov/pubmed/19032770
http://dx.doi.org/10.1186/1471-2172-9-70